Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

• Główni autorzy: Burcu Çalışkan (Autor), Esra Sinoplu (Autor), Kübra İbiş (Autor), Ece Akhan Güzelcan (Autor), Rengül Çetin Atalay (Autor), Erden Banoglu (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

In our endeavour towards the development of effective anticancer therapeutics, a novel series of isoxazole-piperazine hybrids were synthesized and evaluated for their cytotoxic activities against human liver (Huh7 and Mahlavu) and breast (MCF-7) cancer cell lines. Within series, compounds 5l-o showe...