l-Alanine activates hepatic AMP-activated protein kinase and modulates systemic glucose metabolism

• Main Authors: Yusuke Adachi (Author), Ana Luisa De Sousa-Coelho (Author), Ikue Harata (Author), Charlie Aoun (Author), Sandra Weimer (Author), Xu Shi (Author), Karina N. Gonzalez Herrera (Author), Hirokazu Takahashi (Author), Chris Doherty (Author), Yasushi Noguchi (Author), Laurie J. Goodyear (Author), Marcia C. Haigis (Author), Robert E. Gerszten (Author), Mary-Elizabeth Patti (Author)
• Format: Book
• Published: Elsevier, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: AMP activated protein kinase (AMPK) is recognized as an important nutrient sensor contributing to regulation of cellular, tissue, and systemic metabolism. We aimed to identify specific amino acids which could modulate AMPK and determine effects on cellular and systemic metabolism. Methods...