Estrogen Decreases Cytoskeletal Organization by Forming an ERα/SHP2/c-Src Complex in Osteoclasts to Protect against Ovariectomy-Induced Bone Loss in Mice

• Päätekijät: Hyun-Jung Park (Tekijä), Malihatosadat Gholam-Zadeh (Tekijä), Sun-Young Yoon (Tekijä), Jae-Hee Suh (Tekijä), Hye-Seon Choi (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2021-04-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Loss of ovarian function is closely related to estrogen (E₂) deficiency, which is responsible for increased osteoclast (OC) differentiation and activity. We aimed to investigate the action mechanism of E₂ to decrease bone resorption in OCs to protect fro...