Evidence of Insulin-Sensitizing and Mimetic Activity of the Sesquiterpene Quinone Avarone, a Protein Tyrosine Phosphatase 1B and Aldose Reductase Dual Targeting Agent from the Marine Sponge <i>Dysidea avara</i>

• Main Authors: Marcello Casertano (Author), Massimo Genovese (Author), Alice Santi (Author), Erica Pranzini (Author), Francesco Balestri (Author), Lucia Piazza (Author), Antonella Del Corso (Author), Sibel Avunduk (Author), Concetta Imperatore (Author), Marialuisa Menna (Author), Paolo Paoli (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Type 2 diabetes mellitus (T2DM) is a complex disease characterized by impaired glucose homeostasis and serious long-term complications. First-line therapeutic options for T2DM treatment are monodrug therapies, often replaced by multidrug therapies to ensure that non-responding patients maintain targ...