LXR agonist inhibits inflammation through regulating MyD88 mRNA alternative splicing

• Main Authors: Ni Li (Author), Yan Li (Author), Xiaowan Han (Author), Jing Zhang (Author), Jiangxue Han (Author), Xinhai Jiang (Author), Weizhi Wang (Author), Yang Xu (Author), Yanni Xu (Author), Yu Fu (Author), Shuyi Si (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liver X receptors (LXRs) are important regulators of cholesterol metabolism and inflammatory responses. LXR agonists exhibit potently anti-inflammatory effects in macrophages, which make them beneficial to anti-atherogenic therapy. In addition to transrepressive regulation by SUMOylation, LXRs can i...