Inhibitory effects of oxymatrine on hepatic stellate cells activation through TGF-β/miR-195/Smad signaling pathway

Inhibitory effects of oxymatrine on hepatic stellate cells activation through TGF-β/miR-195/Smad signaling pathway

Abstract Background Oxymatrine (OM), a quinolizidine alkaloid extracted from a herb Sophorae Flavescentis Radix, has been used to treat liver fibrotic diseases. However, the mechanism of its anti-fibrosis effects is still unclear. TGF-β/Smad signaling and miR-195 have been proved to paly an importan...

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Main Authors: Li-Ying Song (Author), Yu-Tao Ma (Author), Wei-Jin Fang (Author), Yang He (Author), Jia-Li Wu (Author), Shan-Ru Zuo (Author), Zhen-Zhen Deng (Author), Sheng-Feng Wang (Author), Shi-Kun Liu (Author)
Format: Book
Published: BMC, 2019-06-01T00:00:00Z.
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