PGC1α overexpression preserves muscle mass and function in cisplatin‐induced cachexia

Abstract Background Chemotherapy induces a cachectic‐like phenotype, accompanied by skeletal muscle wasting, weakness and mitochondrial dysfunction. Peroxisome proliferator‐activated receptor‐gamma coactivator‐1 alpha (PGC1α), a regulator of mitochondrial biogenesis, is often reduced in cachectic sk...

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Main Authors: Joshua R. Huot (Author), Fabrizio Pin (Author), Rohit Chatterjee (Author), Andrea Bonetto (Author)
Format: Book
Published: Wiley, 2022-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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