PGC1α overexpression preserves muscle mass and function in cisplatin‐induced cachexia
Abstract Background Chemotherapy induces a cachectic‐like phenotype, accompanied by skeletal muscle wasting, weakness and mitochondrial dysfunction. Peroxisome proliferator‐activated receptor‐gamma coactivator‐1 alpha (PGC1α), a regulator of mitochondrial biogenesis, is often reduced in cachectic sk...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Wiley,
2022-10-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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