Genetically detoxified pertussis toxin induces superior antigen specific CD4 T cell responses compared to chemically detoxified pertussis toxin

Pertussis is resurgent worldwide. Currently available acellular pertussis vaccines contain chemically detoxified pertussis toxin (PTc); a highly immunogenic genetically detoxified pertussis toxin (PTg) vaccine has been off the market for over a decade. We compared CD4+ T cell and B cell responses in...

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Auteurs principaux: Naveen Surendran (Auteur), Michael Pichichero (Auteur)
Format: Livre
Publié: Taylor & Francis Group, 2019-05-01T00:00:00Z.
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