Piperine as Therapeutic Agent in Paracetamol-Induced Hepatotoxicity in Mice

Piperine as Therapeutic Agent in Paracetamol-Induced Hepatotoxicity in Mice

High doses of paracetamol (APAP) can cause irreversible liver damage. Piperine (P) inhibits cytochrome P450, which is involved in the metabolism of various xenobiotics, including paracetamol. We evaluated the hepatoprotective effects of piperine with or without N-acetylcysteine (NAC) in APAP-induced...

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Main Authors: Aline Meireles Coelho (Author), Isabela Ferreira Queiroz (Author), Luiza Oliveira Perucci (Author), Melina Oliveira de Souza (Author), Wanderson Geraldo Lima (Author), André Talvani (Author), Daniela Caldeira Costa (Author)
Format: Book
Published: MDPI AG, 2022-08-01T00:00:00Z.
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