Pharmacokinetics, Tissue Distribution, and Human Serum Albumin Binding Properties of Delicaflavone, a Novel Anti-Tumor Candidate

• Main Authors: Bing Chen (Author), Hongbin Luo (Author), Weiying Chen (Author), Qishu Huang (Author), Kaifan Zheng (Author), Dafen Xu (Author), Shaoguang Li (Author), Ailin Liu (Author), Liying Huang (Author), Yanjie Zheng (Author), Xinhua Lin (Author), Hong Yao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Delicaflavone (DF), a natural active ingredient from Selaginella doederleinii Hieron, has been reported to have favorable anticancer effects and is thus considered a potential anticancer agent. However, its pharmacokinetics and plasma protein binding properties remain unknown. Here, we investigated...