CNP-miR146a Decreases Inflammation in Murine Acute Infectious Lung Injury

• Main Authors: Alyssa E. Vaughn (Author), Tanner Lehmann (Author), Christina Sul (Author), Alison M. Wallbank (Author), Bailey D. Lyttle (Author), James Bardill (Author), Nana Burns (Author), Anisha Apte (Author), Eva S. Nozik (Author), Bradford Smith (Author), Christine U. Vohwinkel (Author), Carlos Zgheib (Author), Kenneth W. Liechty (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute respiratory distress syndrome (ARDS) has approximately 40% in-hospital mortality, and treatment is limited to supportive care. Pneumonia is the underlying etiology in many cases with unrestrained inflammation central to the pathophysiology. We have previously shown that CNP-miR146a, a radical...