CD25 expression could be a prognostic marker of bexarotene monotherapy for cutaneous T‐cell lymphomas

• Main Authors: Jun Yamamoto (Author), Kentaro Ohuchi (Author), Ryo Amagai (Author), Yuna Roh (Author), Junko Endo (Author), Hiromu Chiba (Author), Erika Tamabuchi (Author), Yumi Kambayashi (Author), Akira Hashimoto (Author), Yoshihide Asano (Author), Taku Fujimura (Author)
• Format: Book
• Published: Wiley, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Bexarotene is often administered to phototherapy‐resistant early cutaneous T‐cell lymphoma (CTCL) patients as one of the first‐line therapies in real‐world practice. Since bexarotene reduces the expression of CCR4 in CTCL cells and CCL22 to decrease serum CCL22 levels, bexarotene inhibits t...