Loss of Human Leukocyte Antigen Class I Expression Is Associated with Poor Prognosis in Patients with Advanced Breast Cancer

• Main Authors: Hong Sik Park (Author), Uiju Cho (Author), So Young Im (Author), Chang Young Yoo (Author), Ji Han Jung (Author), Young Jin Suh (Author), Hyun Joo Choi (Author)
• Format: Book
• Published: Korean Society of Pathologists & the Korean Society for Cytopathology, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Human leukocyte antigen class I (HLA-I) molecules play important roles in regulating immune responses. Loss or reduction of HLA-I expression has been shown to be associated with prognosis in several cancers. Regulatory T-cells (Tregs) also play critical functions in immune response regula...