A review of existing strategies for designing long-acting parenteral formulations: Focus on underlying mechanisms, and future perspectives

• Principais autores: Yujie Shi (Autor), An Lu (Autor), Xiangyu Wang (Autor), Zakia Belhadj (Autor), Jiancheng Wang (Autor), Qiang Zhang (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2021-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The need for long-term treatments of chronic diseases has motivated the widespread development of long-acting parenteral formulations (LAPFs) with the aim of improving drug pharmacokinetics and therapeutic efficacy. LAPFs have been proven to extend the half-life of therapeutics, as well as to improv...