Octadecylpropyl Sulfamide Reduces Neurodegeneration and Restores the Memory Deficits Induced by Hypoxia-Ischemia in Mice

• Váldodahkkit: Elk Kossatz (Dahkki), Daniel Silva-Peña (Dahkki), Juan Suárez (Dahkki), Fernando R. de Fonseca (Dahkki), Rafael Maldonado (Dahkki), Patricia Robledo (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The PPAR-α agonist, oleoylethanolamide (OEA) has neuroprotective properties in stroke models. However, its rapid degradation represents a limitation for an effective therapeutic approach. In this study, we evaluated the effects of a stable OEA-modeled compound, octadecylpropyl sulfamide (SUL) on the...