Suppression of ovulation and pharmacokinetics following subcutaneous administration of various doses of Depo-Provera®: a randomized trial

• Main Authors: Vera Halpern (Author), Rachael Fuchs (Author), Vivian Brache (Author), Luis Bahamondes (Author), Maria Jose Miranda (Author), Anja Lendvay (Author), Leila Cochón (Author), Douglas Taylor (Author), Laneta J. Dorflinger (Author)
• Format: Book
• Published: Elsevier, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: To identify the lowest dose of Depo-Provera that, when administered off-label subcutaneously, suppressed ovulation and had a pharmacokinetic profile consistent with a 4-month contraceptive effect.Study Design: We conducted a randomized, multicenter, parallel-group study to evaluate the p...