Evaluation of microsatellite instability in routine examinations of surgical samples
Context: Approximately 20%-30% of colon cancer cases have a hereditary basis. The genetic defect may involve mismatch repair (MMR) genes, which results in microsatellite instability (MSI). MMR-deficient colorectal cancer may occur due to germline mutation (Lynch syndrome) or be a sporadic one. A tum...
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Main Authors: | Pawel Wlaszczuk (Author), Aleksandra Kuzbinska (Author), Zuzanna Dobrosz (Author), Piotr Palen (Author), Krzysztof Pawlicki (Author) |
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Format: | Book |
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Wolters Kluwer Medknow Publications,
2022-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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