TRIB3‒GSK-3β interaction promotes lung fibrosis and serves as a potential therapeutic target

• Main Authors: Shanshan Liu (Author), Xiaoxi Lv (Author), Xupeng Wei (Author), Chang Liu (Author), Qiao Li (Author), Jiali Min (Author), Fang Hua (Author), Xiaowei Zhang (Author), Ke Li (Author), Pingping Li (Author), Yang Xiao (Author), Zhuowei Hu (Author), Bing Cui (Author)
• Format: Book
• Published: Elsevier, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary fibrosis (PF) is a chronic, progressive, fatal interstitial lung disease with limited available therapeutic strategies. We recently reported that the protein kinase glycogen synthase kinase-3β (GSK-3β) interacts with and inactivates the ubiquitin-editing enzyme A20 to suppress the degradat...