Quantitative prediction of pharmacokinetic properties of drugs in humans: Recent advance in in vitro models to predict the impact of efflux transporters in the small intestine and blood-brain barrier

Efflux transport systems are essential to suppress the absorption of xenobiotics from the intestinal lumen and protect the critical tissues at the blood-tissue barriers, such as the blood-brain barrier. The function of drug efflux transport is dominated by various transporters. Accumulated clinical...

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Main Authors: Yoshiki Hashimoto (Author), Kazuyoshi Michiba (Author), Kazuya Maeda (Author), Hiroyuki Kusuhara (Author)
Format: Book
Published: Elsevier, 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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