A Rare Case of Autoimmune Demyelinating Polyneuropathy and Hydrocephalus Secondary to Pembrolizumab

• Hoofdauteurs: Aakriti Arora BS (Auteur), Amar Shere MD (Auteur), Kunal Patel MD (Auteur), Nuwan Gunawardhana MD (Auteur), Ericka LiFuentes MD (Auteur)
• Formaat: Boek
• Gepubliceerd in: SAGE Publishing, 2020-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Pembrolizumab is a humanized monoclonal antibody that targets the programmed cell death 1 protein (PD-1) receptor and blocks the inhibitory checkpoint interaction between PD-1 and its ligands. This interaction leads to the upregulation of effector T-cells and downregulating regulatory T-cell product...