A Rare Case of Autoimmune Demyelinating Polyneuropathy and Hydrocephalus Secondary to Pembrolizumab

• Principais autores: Aakriti Arora BS (Autor), Amar Shere MD (Autor), Kunal Patel MD (Autor), Nuwan Gunawardhana MD (Autor), Ericka LiFuentes MD (Autor)
• Formato: Livro
• Publicado em: SAGE Publishing, 2020-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Pembrolizumab is a humanized monoclonal antibody that targets the programmed cell death 1 protein (PD-1) receptor and blocks the inhibitory checkpoint interaction between PD-1 and its ligands. This interaction leads to the upregulation of effector T-cells and downregulating regulatory T-cell product...