Modeling of endothelial cell dysfunction using human induced pluripotent stem cells derived from patients with end-stage renal disease

• Main Authors: Kyoung Woon Kim (Author), Yoo Jin Shin (Author), Bo-Mi Kim (Author), Sheng Cui (Author), Eun Jeong Ko (Author), Sun Woo Lim (Author), Chul Woo Yang (Author), Byung Ha Chung (Author)
• Format: Book
• Published: The Korean Society of Nephrology, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Endothelial cell (EC) dysfunction is a frequent feature in patients with end-stage renal disease (ESRD). The aim of this study was to generate human induced pluripotent stem cells, differentiate ECs (hiPSC-ECs) from patients with ESRD, and appraise the usefulness of hiPSC-ECs as a model t...