HLA-B allele frequencies and implications for pharmacogenetics in the Kuwaiti population

• Main Authors: Mohammed Dashti (Author), Md Zubbair Malik (Author), Abdullah Al-Matrouk (Author), Saeeda Bhatti (Author), Rasheeba Nizam (Author), Sindhu Jacob (Author), Fahd Al-Mulla (Author), Thangavel Alphonse Thanaraj (Author)
• 格式: 圖書
• 出版: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Objective: This study explores the frequency of human leukocyte antigen (HLA) genes, particularly HLA-B alleles, within the Kuwaiti population. We aim to identify alleles with known associations to adverse drug reactions (ADRs) based on existing literature. We focus on the HLA-B gene due to its well...