Potential Utility of Synthetic D-Lactate Polymers in Skin Cancer

• Main Authors: Anushka Dikshit (Author), Junqi Lu (Author), Amy E. Ford (Author), Simone Degan (Author), Yingai J. Jin (Author), Huiying Sun (Author), Amanda Nichols (Author), April K.S. Salama (Author), Georgia Beasley (Author), David Gooden (Author), Jennifer Y. Zhang (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increased breakdown of glucose through glycolysis in both aerobic and anaerobic conditions is a hallmark feature of mammalian cancer and leads to increased production of L-lactate. The high-level lactate present within the tumor microenvironment is reused as a crucial biofuel to support rapid cancer...