Synthesis and Human Carbonic Anhydrase I, II, IX, and XII Inhibition Studies of Sulphonamides Incorporating Mono-, Bi- and Tricyclic Imide Moieties

New derivatives were synthesised by reaction of amino-containing aromatic sulphonamides with mono-, bi-, and tricyclic anhydrides. These sulphonamides were investigated as human carbonic anhydrases (hCAs, EC 4.2.1.1) I, II, IX, and XII inhibitors. hCA I was inhibited with inhibition constants (Kis)...

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Main Authors: Kalyan K. Sethi (Author), KM Abha Mishra (Author), Saurabh M. Verma (Author), Daniela Vullo (Author), Fabrizio Carta (Author), Claudiu T. Supuran (Author)
Format: Book
Published: MDPI AG, 2021-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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