Transgenic Chlamydomonas Expressing Human Transient Receptor Potential Ankyrin 1 (TRPA1) Channels to Assess the Effect of Agonists and Antagonists

• Main Authors: Megumi Yoshida (Author), Ryodai Yamamiya (Author), Yuto Shimizu (Author), Kenjiro Yoshimura (Author)
• 格式: 图书
• 出版: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Transient receptor potential ankyrin 1 (TRPA1) channel is an ion channel whose gating is controlled by agonists, such as allyl isothiocyanate (AITC), and temperature. Since TRPA1 is associated with various disease symptoms and chemotherapeutic side effects, it is a frequent target of drug developmen...