C57Bl/6N mice have an attenuated lung inflammatory response to dsRNA compared to C57Bl/6J and BALB/c mice

• Autori principali: Sofia Malm Tillgren (Autore), Juan José Nieto-Fontarigo (Autore), Samuel Cerps (Autore), Sangeetha Ramu (Autore), Mandy Menzel (Autore), Irma Mahmutovic Persson (Autore), Anja Meissner (Autore), Hamid Akbarshahi (Autore), Lena Uller (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2023-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background Lower respiratory infections caused by ssRNA viruses are a major health burden globally. Translational mouse models are a valuable tool for medical research, including research on respiratory viral infections. In in vivo mouse models, synthetic dsRNA can be used as a surrogate fo...