C57Bl/6N mice have an attenuated lung inflammatory response to dsRNA compared to C57Bl/6J and BALB/c mice

• Main Authors: Sofia Malm Tillgren (Author), Juan José Nieto-Fontarigo (Author), Samuel Cerps (Author), Sangeetha Ramu (Author), Mandy Menzel (Author), Irma Mahmutovic Persson (Author), Anja Meissner (Author), Hamid Akbarshahi (Author), Lena Uller (Author)
• Format: Book
• Published: BMC, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Lower respiratory infections caused by ssRNA viruses are a major health burden globally. Translational mouse models are a valuable tool for medical research, including research on respiratory viral infections. In in vivo mouse models, synthetic dsRNA can be used as a surrogate fo...