A new and clinically relevant murine model of solid-organ transplant aspergillosis

• Main Authors: Susanne Herbst (Author), Anand Shah (Author), Martin Carby (Author), Gary Chusney (Author), Naresh Kikkeri (Author), Anthony Dorling (Author), Elaine Bignell (Author), Sunil Shaunak (Author), Darius Armstrong-James (Author)
• Format: Book
• Published: The Company of Biologists, 2013-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Invasive fungal infections (IFIs) are a major cause of death in organ transplant patients. The murine hydrocortisone-mediated immunosuppression model of pulmonary aspergillosis is commonly used to characterise IFIs in these patients. However, this model does not take into account the effects...