Impairment by Hypoxia or Hypoxia/Reoxygenation of Nitric Oxide-Mediated Relaxation in Isolated Monkey Coronary Artery: the Role of Intracellular Superoxide

• Main Authors: Masashi Tawa (Author), Kohei Yamamizu (Author), Ayman Geddawy (Author), Takashi Shimosato (Author), Takeshi Imamura (Author), Kazuhide Ayajiki (Author), Tomio Okamura (Author)
• Format: Book
• Published: Elsevier, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: To investigate the effect of hypoxia or hypoxia/reoxygenation on vascular smooth muscle function, mechanical response of monkey coronary artery without endothelium was studied under normoxia, hypoxia, and hypoxia/reoxygenation. Hypoxia or hypoxia/reoxygenation impaired the relaxation by n...