Effects of berberine on acquisition and reinstatement of morphine-induced conditioned place preference in mice

• Main Authors: Faezeh Vahdati Hassani (Author), Mahmoud Hashemzaei (Author), Edris Akbari (Author), Mohsen Imenshahidi (Author), Hossein Hosseinzadeh (Author)
• Format: Book
• Published: Mashhad University of Medical Sciences, 2016-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: It has been shown that berberine, a major component of Berberis vulgaris extract, modulates the activity of several neurotransmitter systems including dopamine (Da) and N-methyl-D-aspartate (NMDA) contributing to rewarding and reinforcing effects of morphine. Drug craving and relapsing ev...