A study of pathological characteristics and BRAF V600E status in Langerhans cell histiocytosis of Vietnamese children

• Main Authors: Thu Dang Anh Phan (Author), Bao Gia Phung (Author), Tu Thanh Duong (Author), Vu Anh Hoang (Author), Dat Quoc Ngo (Author), Nguyen Dinh The Trinh (Author), Tung Thanh Tran (Author)
• Format: Book
• Published: Korean Society of Pathologists & the Korean Society for Cytopathology, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Langerhans cell histiocytosis (LCH) is more common in children than adults and involves many organs. In children, the BRAF V600E mutation is associated with recurrent and high-risk LCH. Methods We collected paraffin blocks of 94 pediatric LCH patients to detect BRAF_V600E mutation by sequ...