Challenges encountered with argatroban anticoagulation during cardiopulmonary bypass

• Main Authors: Shvetank Agarwal (Author), Beth Ullom (Author), Yasser Al-Baghdadi (Author), Michael Okumura (Author)
• 格式: 圖書
• 出版: Wolters Kluwer Medknow Publications, 2012-01-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Use of argatroban as an alternative to heparin during cardiopulmonary bypass (CPB) in patients with heparin-induced thrombocytopenia has gained some attention in the past two decades. Dosing of argatroban during CPB is complex due to lack of complete understanding of its pharmacokinetic profile and...