NUC041, a Prodrug of the DNA Methytransferase Inhibitor 5-aza-2',2'-Difluorodeoxycytidine (NUC013), Leads to Tumor Regression in a Model of Non-Small Cell Lung Cancer
5-aza-2′,2′-difluorodeoxycytidine (NUC013) has been shown to be significantly safer and more effective than decitabine in xenograft models of human leukemia and colon cancer. However, it suffers from a similar short half-life as other DNA methyltransferase inhibitors with a 5-aza...
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| Main Authors: | , , |
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| Format: | Book |
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MDPI AG,
2018-04-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |