An exposure‐response analysis of ponesimod clinical efficacy in a randomized phase III study in patients with relapsing multiple sclerosis

• Main Authors: Belén Valenzuela (Author), Per Olsson Gisleskog (Author), Italo Poggesi (Author), Tatiana Sidorenko (Author), Michel Burcklen (Author), Hilke Kracker (Author), Juan Jose Pérez‐Ruixo (Author)
• Format: Book
• Published: Wiley, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The efficacy of ponesimod and teriflunomide for the treatment of relapsing multiple sclerosis (MS) was compared in a randomized phase III trial. This study explores the exposure‐response (E‐R) relationships of efficacy end points (annualized relapse rate [ARR] and combined unique active les...