Isoxazol-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors

Isoxazol-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors

Human neutrophil elastase (HNE) is an important target for the development of novel and selective inhibitors to treat inflammatory diseases, especially pulmonary pathologies. Here, we report the synthesis, structure-activity relationship analysis, and biological evaluation of a new series of HNE inh...

Full description

Saved in:
Bibliographic Details
Main Authors: Claudia Vergelli (Author), Igor A. Schepetkin (Author), Letizia Crocetti (Author), Antonella Iacovone (Author), Maria Paola Giovannoni (Author), Gabriella Guerrini (Author), Andrei I. Khlebnikov (Author), Samuele Ciattini (Author), Giovanna Ciciani (Author), Mark T. Quinn (Author)
Format: Book
Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items