Mitochondrial-Targeted Antioxidant MitoQ-Mediated Autophagy: A Novel Strategy for Precise Radiation Protection

• Main Authors: Xingting Bao (Author), Xiongxiong Liu (Author), Qingfeng Wu (Author), Fei Ye (Author), Zheng Shi (Author), Dan Xu (Author), Jinhua Zhang (Author), Zhihui Dou (Author), Guomin Huang (Author), Hong Zhang (Author), Chao Sun (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiotherapy (RT) is one of the most effective cancer treatments. However, successful radiation protection for normal tissue is a clinical challenge. Our previous study observed that MitoQ, a mitochondria-targeted antioxidant, was adsorbed to the inner mitochondrial membrane and remained the cationi...