Haplotype analysis of BRCA1 intragenic markers in Iranian patients with familial breast and ovarian cancer

• 主要な著者: Seyed Mohsen Miresmaeili (著者), Dor Mohammad Kordi Tamandani (著者), Seyed Mehdi Kalantar (著者), Seyed Mohammad Moshtaghioun (著者)
• フォーマット: 図書
• 出版事項: Shahid Sadoughi University of Medical Science, Yazd, Iran, 2016-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background: Breast cancer is the most common malignancy in women. Breast Cancer Type 1 Susceptibility gene (BRCA1) is a tumor suppressor gene, involved in DNA damage repair and in 81% of the breast-ovarian cancer families were due to BRCA1. In some clinically investigated genes, the intragenic marke...