Effective relief of neuropathic pain by adeno-associated virus-mediated expression of a small hairpin RNA against GTP cyclohydrolase 1

• Main Authors: Chang Jin (Author), Kim Dong (Author), Lee Yoon (Author), Lee Won (Author), Kim Sung (Author), Kim Seong (Author), Lee Heuiran (Author)
• Format: Book
• Published: SAGE Publishing, 2009-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Recent studies show that transcriptional activation of GTP cyclohydrolase I (GCH1) in dorsal root ganglia (DRG) is significantly involved in the development and persistency of pain symptoms. We thus hypothesize that neuropathic pain...