Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy

• Main Authors: Ubaldina Galli (Author), Giorgia Colombo (Author), Cristina Travelli (Author), Gian Cesare Tron (Author), Armando A. Genazzani (Author), Ambra A. Grolla (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nicotinamide adenine dinucleotide (NAD) is a cofactor of many enzymatic reactions as well as being a substrate for a number of NAD-consuming enzymes (e.g., PARPS, sirtuins, etc). NAD can be synthesized de novo starting from tryptophan, nicotinamide, nicotinic acid, or nicotinamide riboside from the...