Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy
Nicotinamide adenine dinucleotide (NAD) is a cofactor of many enzymatic reactions as well as being a substrate for a number of NAD-consuming enzymes (e.g., PARPS, sirtuins, etc). NAD can be synthesized de novo starting from tryptophan, nicotinamide, nicotinic acid, or nicotinamide riboside from the...
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Frontiers Media S.A.,
2020-05-01T00:00:00Z.
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