Kinetics of myelin breakdown products: A labeling study in patients with progressive multiple sclerosis

• Glavni autori: Kawita M. S. Kanhai (Autor), Sebastiaan C. Goulooze (Autor), Jeroen van derGrond (Autor), Amy C. Harms (Autor), Thomas Hankemeier (Autor), Ajay Verma (Autor), Gersham Dent (Autor), Juan Chavez (Autor), Henri Meijering (Autor), Geert Jan Groeneveld (Autor)
• Format: Knjiga
• Izdano: Wiley, 2022-03-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract The majority of disease modifying therapies for multiple sclerosis (MS) reduce inflammation, but do no't target remyelination. Development of remyelinating therapies will benefit from a method to quantify myelin kinetics in patients with MS. We labeled myelin in vivo with deuterium, an...