Hyaluronan and Reactive Oxygen Species Signaling-Novel Cues from the Matrix?

• Main Authors: Aikaterini Berdiaki (Author), Monica Neagu (Author), Ioanna Spyridaki (Author), Andrey Kuskov (Author), Serge Perez (Author), Dragana Nikitovic (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hyaluronan (HA) is a naturally occurring non-sulfated glycosaminoglycan (GAG) localized to the cell surface and the tissue extracellular matrix (ECM). It is composed of disaccharides containing glucuronic acid and N-acetylglucosamine, is synthesized by the HA synthase (HAS) enzymes and is degraded b...