Association of plasma levetiracetam concentration, MGMT methylation and sex with survival of chemoradiotherapy-treated glioblastoma patients

• Main Authors: Federico Cucchiara (Author), Giacomo Luci (Author), Noemi Giannini (Author), Filippo Sean Giorgi (Author), Paola Orlandi (Author), Marta Banchi (Author), Antonello Di Paolo (Author), Francesco Pasqualetti (Author), Romano Danesi (Author), Guido Bocci (Author)
• Format: Book
• Published: Elsevier, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioblastoma multiforme (GBM) is an aggressive brain tumor, often occurring with seizures managed with antiepileptic drugs, such as levetiracetam (LEV). This study is aimed at associating progression-free survival (PFS) and overall survival (OS) of GBM patients with LEV plasma concentration, MGMT pr...