Iron Oxide Nanoparticles Carrying 5-Fluorouracil in Combination with Magnetic Hyperthermia Induce Thrombogenic Collagen Fibers, Cellular Stress, and Immune Responses in Heterotopic Human Colon Cancer in Mice

• Principais autores: Mohammad Dabaghi (Autor), Seyed Mohammad Mahdi Rasa (Autor), Emilio Cirri (Autor), Alessandro Ori (Autor), Francesco Neri (Autor), Rainer Quaas (Autor), Ingrid Hilger (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2021-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

In this study we looked for the main protein pathway regulators which were responsible for the therapeutic impact on colon cancers when combining magnetic hyperthermia with the chemotherapeutic agent 5-fluorouracil (5FU). To this end, chitosan-coated magnetic nanoparticles (MNP) functionalized with...