In Vitro Evaluation of a Solid Supersaturated Self Nanoemulsifying Drug Delivery System (Super-SNEDDS) of Aprepitant for Enhanced Solubility

• Autori principali: Hakan Nazlı (Autore), Burcu Mesut (Autore), Yıldız Özsoy (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2021-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Aprepitant (APR) belongs to Class II of the Biopharmaceutical Classification System (BCS) because of its low aqueous solubility. The objective of the current work is to develop self-nanoemulsifying drug delivery systems (SNEDDS) of APR to enhance its aqueous solubility. Preformulation studies involv...