Angiogenesis-Related Cytokines, RANKL, and Osteoprotegerin in Multiple Myeloma Patients in relation to Clinical Features and Response to Treatment

• Main Authors: K. Sfiridaki (Author), C. A. Pappa (Author), G. Tsirakis (Author), P. Kanellou (Author), M. Kaparou (Author), M. Stratinaki (Author), G. Sakellaris (Author), G. Kontakis (Author), M. G. Alexandrakis (Author)
• Format: Book
• Published: Hindawi Limited, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An essential cytokine system for the osteoclast biology in multiple myeloma (MM) consists of the receptor of activator of NF-κB ligand (RANKL), its receptor (RANK), and the soluble decoy receptor, osteoprotegerin (OPG). Myeloma cells cause imbalance in OPG/RANKL interactions. We measured serum level...