Multiplex Genome Editing in Chinese Hamster Ovary Cell Line Using All-in-One and HITI CRISPR Technology

• Main Authors: Fatemeh Safari (Author), Safar Farajnia (Author), Younes Ghasemi (Author), Nosratollah Zarghami (Author), Mazyar Barekati Mowahed (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: CRISPR/Cas9 gene editing technology has revolutionized gene manipulation by providing the opportunity of gene knock out/in, transcriptional modification and base editing. The application of this system extended into different eras of biology, from cell development to animal modeling. Variou...