Melatonin ameliorates age-related sarcopenia by inhibiting fibrogenic conversion of satellite cell

• Main Authors: Guo-Zheng Zhu (Author), Kai Zhao (Author), Hong-Zhou Li (Author), Di-Zheng Wu (Author), Yun-Biao Chen (Author), Dong Han (Author), Jia-Wen Gao (Author), Xing-Yu Chen (Author), Yong-Peng Yu (Author), Zhi-Wei Huang (Author), Chen Tu (Author), Zhao-Ming Zhong (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The fibrogenic conversion of satellite cells contributes to the atrophy and fibrosis of skeletal muscle, playing a significant role in the pathogenesis of age-related sarcopenia. Melatonin, a hormone secreted by the pineal gland, exhibits anti-aging and anti-fibrotic effects in various cond...