Impact of Insulin Tregopil and Its Permeation Enhancer on Pharmacokinetics of Metformin in Healthy Volunteers: Randomized, Open‐Label, Placebo‐Controlled, Crossover Study

• প্রধান লেখক: Anand Khedkar (লেখক), Harold Lebovitz (লেখক), Alexander Fleming (লেখক), Alan Cherrington (লেখক), Vinu Jose (লেখক), Sandeep N. Athalye (লেখক), Ashwini Vishweswaramurthy (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2019-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Oral insulin tregopil (IN‐105; a new drug under development) may be coadministered with oral antidiabetic drugs, such as metformin in patients with type 2 diabetes mellitus for optimal glycemic control. IN‐105 has sodium caprate excipient, a permeation enhancer, for enhancing absorption in the stoma...