Targeting Insulin Receptor with a Novel Internalizing Aptamer

• Κύριοι συγγραφείς: Margherita Iaboni (Συγγραφέας), Raffaela Fontanella (Συγγραφέας), Anna Rienzo (Συγγραφέας), Maria Capuozzo (Συγγραφέας), Silvia Nuzzo (Συγγραφέας), Gianluca Santamaria (Συγγραφέας), Silvia Catuogno (Συγγραφέας), Gerolama Condorelli (Συγγραφέας), Vittorio de Franciscis (Συγγραφέας), Carla Lucia Esposito (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2016-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Nucleic acid-based aptamers are emerging as therapeutic antagonists of disease-associated proteins such as receptor tyrosine kinases. They are selected by an in vitro combinatorial chemistry approach, named Systematic Evolution of Ligands by Exponential enrichment (SELEX), and thanks to their small...