Formulated Phospholipids as Non-Canonical TLR4 Agonists

• Päätekijät: Hong Liang (Tekijä), William R. Lykins (Tekijä), Emilie Seydoux (Tekijä), Jeffrey A. Guderian (Tekijä), Tony Phan (Tekijä), Christopher B. Fox (Tekijä), Mark T. Orr (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2022-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Immunogenic agents known as adjuvants play a critical role in many vaccine formulations. Adjuvants often signal through Toll-like receptor (TLR) pathways, including formulations in licensed vaccines that target TLR4. While TLR4 is predominantly known for responding to lipopolysaccharide (LPS), a com...